"I found a Phase III trial for my LVEF in eleven minutes. My cardiologist didn't know it existed."
Your heart condition has been studied more than you've been told.
Over 90 active cardiac trials are enrolling right now. Most patients never hear about them. Match finds the ones you qualify for — in the time it takes to drink a glass of water.
Every question you're afraid to ask. Answered first.
We built this page for the person who types "clinical trial scam" into Google at 2 a.m. Skepticism is the right starting point.
“How do you actually find trials that match me?”
We read your condition, not just your keyword
You select your diagnosis and current treatments. Our filters cross-reference active ClinicalTrials.gov records against LVEF thresholds, NYHA class, medication history, and zip code — the same variables a trial coordinator would screen for.
“Will I get a sugar pill instead of real treatment?”
Placebo use is disclosed before you see any result
Every trial result shows whether it is placebo-controlled and what the control arm receives. In cardiac trials, placebo is almost always given alongside your existing standard-of-care medications — not instead of them. You never stop your current treatment.
“What does "Phase III" actually mean for me?”
Phase tells you how far the treatment has already been tested
Phase I: safety only, small group (20–80 people). Phase II: does it work, medium group. Phase III: large-scale comparison against standard care — the closest thing to a proven treatment before FDA approval. 59.9% of cardiac trials are Phase III.
“Can I leave if I change my mind?”
You can withdraw at any time, for any reason, with no penalty
Informed consent is not a contract. You can stop participating at any point — mid-trial, mid-treatment cycle, whenever. Your existing care and relationship with your doctor cannot be affected by your decision to withdraw.
“What happens after I find a match?”
You get a printable summary to bring to your next appointment
Every matched trial generates a one-page summary with the trial name, NCT number, principal investigator contact, eligibility criteria, and nearest enrolling site. Print it, email it, or share it directly with your cardiologist — no account required.
Still have questions? Download the free Patient's Guide to Cardiac Trials →
What you deserve to know before you decide.
The therapeutic misconception — believing a trial is the same as treatment — is the most common source of patient anxiety. Here's the honest version.
A trial is a structured study — not an experiment on you
Clinical trials are the method by which every drug your cardiologist prescribes was proven to work. They follow strict federal protocols with oversight boards that can stop a trial at any moment if participants are harmed.
- FDA requires Institutional Review Board (IRB) approval before any trial begins
- You receive written informed consent — not verbal, not implied
- Independent Data Safety Monitoring Board reviews interim results
- You keep all your existing care throughout
"Placebo-controlled" in cardiac trials almost always means add-on, not replacement
In nearly all cardiac trials, the placebo group continues receiving their standard medications. The placebo tests whether the new treatment adds benefit on top of existing care — not whether it replaces it.
- EMPEROR-PRESERVED: placebo group still received all standard HFpEF medications
- DELIVER trial: same protocol — no patient stopped their cardiologist-prescribed drugs
- If a proven treatment exists, withholding it for placebo requires explicit ethical justification
- DSMB can halt the trial early if placebo arm shows risk
You are a partner in research, not a subject
Federal law (45 CFR 46) guarantees every trial participant the right to full information, the right to ask questions at any time, and the unconditional right to withdraw — with no effect on your ongoing medical care.
- Right to understand: all procedures explained in plain language before you consent
- Right to ask: you can request answers from the research team at any time
- Right to refuse: saying no changes nothing about your current treatment
- Right to leave: withdrawal at any stage, no reason required
Trials span HFrEF, HFpEF, AFib, CAD, valve disease, hypertrophic cardiomyopathy, and ATTR-CM. Phase I through Phase III.
Find trials for your condition.
Three steps. No account required. Results in under 90 seconds.
The Patient's Guide to Cardiac Clinical Trials
Written for patients, not researchers. Plain language. No jargon. Everything you need to walk into a trial conversation feeling prepared — not pressured.
- What questions to ask your cardiologist about trials
- How to read an eligibility criteria list
- The difference between Phase II and Phase III
- Your rights under 45 CFR 46 — plain language version
- How to withdraw from a trial safely
- What to bring to an enrollment appointment
- How to find a second opinion before enrolling
Request a referral pathway summary for your practice — formatted for EMR notes. Contact us →